Actos is a brand name for the prescription medication pioglitazone hydrochloride that is used to treat type 2, or adult-onset, diabetes mellitus. Unlike ot…
Actos is a brand name for the prescription medication pioglitazone hydrochloride that is used to treat type 2, or adult-onset, diabetes mellitus. It may be used alone or with other medications when diet and exercise are not enough to control blood sugar levels. Unlike other diabetes medications, Actos does not cause hypoglycemia or very low blood sugar levels, but it does have other side effects and benefits in the body.
Mechanism of Action Insulin is a hormone that is essential to transport glucose or sugars in the blood to the cells of the body where they can be used for energy or stored. When the body develops a resistance to insulin, Type 2 diabetes mellitus can result. In this disease, there may be enough insulin but decreased sensitivity to it. Actos also acts by inhibiting hepatic gluconeogenesis or glucose production by the liver. This helps to decrease hyperglycemia or high levels of glucose in the blood to control the symptoms of Type 2 diabetes.
Because it is an oral medication that can be used in conjunction with other medications, such as metformin, insulin or sulfonylureas. Instead of adding glucose or reducing insulin resistance, Actos helps the body use insulin more efficiently. You can take the medicine with or without food. It comes in three dosage levels that will be prescribed by your doctor to suit your medical needs.
Caution Use of Actos may lead to swelling and weight gain. This may have a detrimental affect on patient health placing you at higher risk of cardiovascular issues, including heart failure. Although this drug can lower triglycerides it may increase LDL cholesterol, further increasing the risk of coronary heart disease. Long-term use may increase risk of liver problems.
As it affects the hormone insulin, an endocrine or hormonal side effect in the body includes mild or moderate hypoglycemia or low blood sugar. As the body uses insulin more effectively with the help of this medication, more glucose is transferred from the blood to the body muscles and tissues.
Some people should not take Actos(pioglitazone hydrochloride, 112529-15-4) for their diabetes treatment. People with Type 1 diabetes are advised against taking it, as are those who regularly experience diabetic ketoacidosis. If you currently have or think you may have liver disease, then this medicine may not be for you.
Costs While Actos is effective for type 2 diabetes, it is more expensive than many other oral diabetes medications. If you are using it, expect to pay between $90 to $250 each month for your medications, depending on your insurance program. This is similar to other high-priced medications such as Avandia, Symilin and Byetta. Lower-priced medications range from $4 to $100 per month and include Glucotrol, Amaryl and Fortamet.